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Key Documents

T3705

Sigma-Aldrich

Transferrin human

Optiferrin, recombinant, expressed in rice

Synonym(s):

Optiferrin

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.61

biological source

human

Quality Level

recombinant

expressed in rice

Assay

≥95% (agarose gel electrophoresis)

form

powder

composition

Protein, ≥90%

Iron content

≥300 μg/g

technique(s)

immunoprecipitation (IP): suitable
tissue culture: suitable

impurities

≤1.0 EU/mg Endotoxin

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... TF(7018)

General description

Transferrin is an 80 kDa serum glycoprotein, which is expressed in hepatocytes. The gene is located on human chromosome 3q22.1.
Optiferrin is recombinant human transferrin that is completelyblood-free. Optiferrin’s performance is equivalent to human holo transferrin incell culture and offers significant regulatory advantages due to its safety andconsistency. Optiferrin is suitable for a broad range of cell types thatinclude stem, primary, and bioproduction cells.

Application

Transferrin Human has been used to perform immunoprecipitation measurements. It has also been used for the preparation of essential 8 medium.

Biochem/physiol Actions

Human transferrin was shown to promote allogeneic chimerism in mice after irradiation and transplantation of incompatible bone marrow.
Transferrin facilitates the transfer of iron to erythron and peripheral tissues. It stimulates the proliferation of human lymphocytes. Mutations in this gene are linked to atransferrinemia.

Other Notes

1). Patent Rights
U.S. Patent No. 9,321,828
2). Registered Trademark Rights
U.S. Reg. 3,880,881
International Reg. 1,466,509

Legal Information

Optiferrin is a trademark of InVitria

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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