SAE0082
Lipodisq® Styrene:Maleic Anhydride Copolymer 4:1, Pre-hydrolyzed
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.25
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General description
This product is the pre-hydrolyzed form of the Styrene:Maleic Anhydride Copolymer 4:1. It can be regarded, in effect, as Styrene:Maleic Acid Copolymer 4:1 (SMA Copolymer 4:1).
Application
Lipodisq reagents are novel polymers derived from styrene and maleic acid. Lipodisq polymers are capable of forming nanosized lipid-based discoidal particles capable of incorporating membrane proteins. The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents. Lipodisqs typically have a diameter of 9-10 nm at pH 7.4.
The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents.
Functional pH range: 8.5 - 10.5
The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents.
Functional pH range: 8.5 - 10.5
Legal Information
Lipodisq is a registered trademark of Malvern Cosmeceutics Limited
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Juan Francisco Bada Juarez et al.
Chemistry and physics of lipids, 221, 167-175 (2019-04-04)
Nanoparticles assembled with poly(styrene-maleic acid) copolymers, identified in the literature as Lipodisq, SMALPs or Native Nanodisc, are routinely used as membrane mimetics to stabilise protein structures in their native conformation. To date, transmembrane proteins of varying complexity (up to 8
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