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Key Documents

SAB5702555

Sigma-Aldrich

Anti-PER2 Antibody, clone 2K9Y0, Rabbit Monoclonal

Synonym(s):

FASPS, FASPS1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

material

colorless

clone

2K9Y0, monoclonal

form

liquid

mol wt

140 kDa

species reactivity

mouse, mouse

concentration

0.6 mg/mL

technique(s)

ChIP: 1:50 - 1:200
immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

MNGYAEFPPSPSNPTKEPVEPQPSQVPLQEDVDMSSGSSGHETNENCSTGRDSQGSDCDDSGKELGMLVEPPDARQSPDTFSLMMAKSEHNPSTSGCSSD

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PER2(8864)

General description

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders. [provided by RefSeq, Jan 2014]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PER2 (O15055).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IF/ICC, ChIP

Storage Class Code

10 - Combustible liquids

WGK

WGK 1


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