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Key Documents

SAB4700052

Sigma-Aldrich

Monoclonal Anti-CD247 azide free antibody produced in hamster

clone H146-968, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-CD247, Anti-CD3-Ζ

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

hamster

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

H146-968, monoclonal

form

buffered aqueous solution

species reactivity

mouse, human

concentration

1 mg/mL

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_000734.3

UniProt accession no.

P20963

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... CD247(919)

General description

The hamster antibody H146-968 reacts with CD3 zeta chain (CD247), which is a component of TCR/CD3 complex expressed on T cells.

Immunogen

Synthetic peptide corresponding to amino acids 151-164 of mouse CD3 zeta

Application

Suggested working dilution for immunoblotting is 1 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in azide free phosphate buffered saline, pH 7.4; 0.2 um filter sterilized.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Philip O Scumpia et al.
Blood, 110(10), 3673-3681 (2007-08-11)
Apoptosis of CD4(+) T cells and T(H)2 polarization are hallmarks of sepsis-induced immunoparalysis. In this study, we characterized sepsis-induced adaptive immune dysfunction and examined whether improving T-cell effector function can improve outcome to sepsis. We found that septic mice produced

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