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R6153

Sigma-Aldrich

Monoclonal Anti-RhoE antibody produced in mouse

~2 mg/mL, clone 4, purified immunoglobulin, aqueous solution

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

4, monoclonal

form

aqueous solution

mol wt

antigen ~29 kDa

species reactivity

human, mouse

concentration

~2 mg/mL

technique(s)

immunocytochemistry: suitable
microarray: suitable
western blot: 4-8 μg/mL using HMVEC total cell extract.

isotype

IgG1

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RND3(390)
mouse ... Rnd3(74194)

Specificity

The antibody weakly cross reacts with Rnd1.

Immunogen

purified recombinant full length RhoE.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Raquel Talens-Visconti et al.
Journal of neurochemistry, 112(4), 1074-1087 (2009-12-09)
Neurite formation involves coordinated changes between the actin cytoskeleton and the microtubule network. Rho GTPases are clearly implicated in several aspects of neuronal development and function. Indeed, RhoA is a negative regulator of neurite outgrowth and its effector Rho-kinase mediates
Kirsi Riento et al.
Molecular and cellular biology, 23(12), 4219-4229 (2003-05-30)
RhoE belongs to the Rho GTPase family, the members of which control actin cytoskeletal dynamics. RhoE induces stress fiber disassembly in a variety of cell types, whereas RhoA stimulates stress fiber assembly. The similarity of RhoE and RhoA sequences suggested
Xi Chen et al.
Journal of cellular physiology, 235(1), 221-231 (2019-06-13)
The motility of mesenchymal stem cells (MSCs) is highly related to their homing in vivo, a critical issue in regenerative medicine. Our previous study indicated copper (Cu) might promote the recruitment of endogenous MSCs in canine esophagus defect model. In
Yajie Zhu et al.
International journal of oncology, 44(3), 896-904 (2014-01-09)
Previous studies have shown that RhoE, an atypical member of the Rho GTPase family, may play an opposite role to RhoA in regulating cell proliferation and invasion. To explore the relationship between RhoE and the malignant phenotypes of human cancer

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