Q1004

Quipazine maleate salt

• Synonym(s): 2-(1-Piperazinyl)quinoline maleate salt
• Empirical Formula (Hill Notation): C₁₃H₁₅N₃ · C₄H₄O₄
• CAS Number: 5786-68-5
• Molecular Weight: 329.35
• EC Number: 227-314-2
• MDL number: MFCD00133796
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278122
• NACRES: NA.77

Properties

• solubility: H₂O: soluble; alcohol: soluble; dilute aqueous acid: soluble
• Quality Level: 200
• storage temp.: 2-8°C
• SMILES string: OC(=O)\C=C/C(O)=O.C1CN(CCN1)c2ccc3ccccc3n2
• InChI: 1S/C13H15N3.C4H4O4/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16;5-3(6)1-2-4(7)8/h1-6,14H,7-10H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI key: QYJJDHZHSCTBII-BTJKTKAUSA-N
• Gene Information: human ... HTR1A(3350) , HTR1B(3351) , HTR1D(3352) , HTR1E(3354) , HTR1F(3355) , HTR2A(3356) , HTR2B(3357) , HTR2C(3358) , HTR3A(3359) , HTR3B(9177) , HTR3C(170572) , HTR3D(200909) , HTR3E(285242) , HTR4(3360) , HTR5A(3361) , HTR5B(645694) , HTR6(3362) , HTR7(3363)

Description

Application

Quipazine maleate salt has been used as a serotonin receptor agonist to study its effects on mouse models with spinal cord injury. It has also been used as a serotonin receptor agonist to study its effects on the locomotion of zebrafish.

Biochem/physiol Actions

Quipazine belongs to the class of psychedelics and acts as a serotonin/5-hydroxytryptamine-2A/C receptor agonist. It also acts as an inhibitor of prolactin.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301
• Precautionary Statements: P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves