P5386

Poly-γ-benzyl-L-glutamate

mol wt 70,000-150,000

• Synonym(s): PBLG
• CAS Number: 25014-27-1
• MDL number: MFCD00166357
• UNSPSC Code: 12352200
• NACRES: NA.26

Properties

• form: powder
• Quality Level: 200
• mol wt: 70,000-150,000
• color: white to light yellow
• storage temp.: −20°C
• InChI: 1S/C12H15NO4/c13-10(12(15)16)6-7-11(14)17-8-9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,15,16)/t10-/m0/s1
• InChI key: BGGHCRNCRWQABU-JTQLQIEISA-N

Description

Application

• Hydrogen bond formation may enhance RDC-based discrimination of enantiomers.: This research explores the impact of hydrogen bond formation on residual dipolar couplings (RDC) in the discrimination of enantiomers. Poly-y-benzyl-L-glutamate (PBLG) is used as a chiral alignment medium, enhancing the sensitivity and resolution of NMR spectroscopy for enantiomeric analysis (Sager et al., 2024).


• Potential and performance of anisotropic (19)F NMR for the enantiomeric analysis of fluorinated chiral active pharmaceutical ingredients.: This study highlights the use of PBLG as an alignment medium in anisotropic 19F NMR spectroscopy for analyzing chiral pharmaceutical compounds. The research demonstrates improved enantiomeric discrimination and quantification, crucial for pharmaceutical development (Gouilleux et al., 2024).


• Block Sequence Effects on the Self-Assembly Behaviors of Polypeptide-Based Penta-Block Copolymer Hydrogels.: This study investigates the self-assembly behavior of block copolymer hydrogels containing PBLG. The research shows how block sequence affects the mechanical properties and potential applications of these hydrogels in biomedical fields (Wang et al., 2024).


• Liquid crystalline composite hydrogels with large pH-triggered anisotropic swelling for embolotherapy.: This research explores the development of liquid crystalline hydrogels incorporating PBLG for use in embolotherapy. The hydrogels demonstrate significant pH-responsive swelling, making them suitable for targeted medical applications (Zhang et al., 2024).

Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves