P0496

Anti-PTX3 antibody produced in rabbit

affinity isolated antibody, ammonium sulfate suspension

• Synonym(s): Anti-AI607804, Anti-LOC682447, Anti-PTX3, Anti-TNFAIP5, Anti-TSG-14, Anti-pentraxin 3
• MDL number: MFCD03097187
• UNSPSC Code: 12352203
• NACRES: NA.41
• conjugate: unconjugated
• application: IHC; WB
• clone: polyclonal
• species reactivity: rodent, human
• citations: 6
• technique(s): immunohistochemistry: suitable; western blot: suitable

Properties

• biological source: rabbit
• Quality Level: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: ammonium sulfate suspension
• mol wt: antigen 31.8 kDa
• species reactivity: rodent, human
• technique(s): immunohistochemistry: suitable; western blot: suitable
• UniProt accession no.: P26022
• storage temp.: −20°C
• Gene Information: human ... PTX3(5806) ; mouse ... Ptx3(19288) ; rat ... Ptx3_mapped(116998)

Description

General description

The PTX3 (pentraxin 3) gene is mapped to human chromosome 3q25.32. The protein is localized in mesenchymal cells, endothelial cells of vascular tissue, fibroblasts, monocytes and granulocytes.

Immunogen

a synthetic peptide corresponding to human PTX3 (amino acids 110-124) conjugated to BSA.

Application

Anti-PTX3 antibody produced in rabbit has been used in immunofluorescence and immunohistochemistry.

Biochem/physiol Actions

PTX3 (pentraxin 3) is associated with humoral immune response and inflammatory processes, and therefore offers protection against pathogenic antigens. Proinflammatory cytokines, microbes and signals derived from damaged tissue triggers the expression of the gene upon stimulation. It serves as a biomarker for a number of inflammatory vascular and autoimmune disorders, including vasculitis, rheumatoid arthritis, psoriasis, and cardiovascular diseases. PTX3 is involved in tumor progression by participating in proliferation and invasion steps, which were observed in glioma.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable