L7895

Lipopolysaccharides from Salmonella typhosa

γ-irradiated, BioXtra, suitable for cell culture

• Synonym(s): LPS
• MDL number: MFCD00131520
• UNSPSC Code: 12352201
• NACRES: NA.75

Properties

• biological source: bacterial (Salmonella typhosa)
• Quality Level: 200
• sterility: γ-irradiated
• product line: BioXtra
• form: lyophilized powder
• purified by: gel-filtration chromatography
• technique(s): cell culture | mammalian: suitable
• impurities: <1% Protein (Lowry)
• color: white to faint yellow
• solubility: water: 0.90-1.10 mg/mL, faintly hazy to hazy, colorless to faintly yellow
• storage temp.: 2-8°C

Description

Application

Lipopolysaccharides from Salmonella typhosa are used in cell culture and cell binding applications. The role of LPS in the secretion of TNF-α and IL-6 was studied in mouse spleen cell culture. It was used to study the role of inflammatory responses in multiple sclerosis.

Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).

Biochem/physiol Actions

Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).

Other Notes

To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves