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Application
Hydroxyalkoxypropyl-Dextran is used for liquid chromatography, protein chromatography, and gel filtration chromatography. Hydroxyalkoxypropyl-Dextran has been used to develop a nondestructive method for effective removal of lipids from small quantities of aqueous protein as well as to develop a highly specific method for the determination of cortisol in human serum and urine.
Lipophilic, hydrophobic gel for liquid chromatography.
Other Notes
Hydroxypropyl beaded dextran (Lipophilic Sephadex, LH-20-100), substituted with long chain alkyl ethers.
Substituted approx. 10% by weight with alkyl chains of length C15-C18
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Gregory P Tochtrop et al.
Journal of the American Chemical Society, 126(35), 11024-11029 (2004-09-02)
The recognition between proteins and their native ligands is fundamental to biological function. In vivo, human ileal bile acid binding protein (I-BABP) encounters a range of bile salts that vary in the number and position of steroidal hydroxyl groups and
Mariana Suárez et al.
PloS one, 15(11), e0242312-e0242312 (2020-11-13)
The intestinal fatty acid binding protein (FABP) is a small protein expressed along the small intestine that bind long-chain fatty acids and other hydrophobic ligands. Several lines of evidence suggest that, once in the nucleus, it interacts with nuclear receptors
Gergő Horváth et al.
The FEBS journal, 283(3), 541-555 (2015-11-28)
Besides aiding digestion, bile salts are important signal molecules exhibiting a regulatory role in metabolic processes. Human ileal bile acid binding protein (I-BABP) is an intracellular carrier of bile salts in the epithelial cells of the distal small intestine and
Gregory P Tochtrop et al.
Biochemistry, 42(40), 11561-11567 (2003-10-08)
Human ileal bile acid binding protein (I-BABP) is a member of the intracellular lipid binding protein family. This protein is thought to function in the transcellular transport and enterohepatic circulation of bile salts. Human I-BABP binds two molecules of glycocholate
Christophe Anjard et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(21), 7607-7611 (2005-05-18)
A wide variety of mechanisms have evolved for intercellular communication in metazoans, but some of the signaling molecules were already used in their predecessors. The social amoeba, Dictyostelium discoideum, is known to use peptides to trigger sporulation within fruiting bodies
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