GW22500
Anti-Interleukin-17a antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
clone:
polyclonal
application:
ELISA (i)
WB
WB
species reactivity:
human
technique(s):
indirect ELISA: suitable
western blot: suitable
western blot: suitable
citations:
5
biological source
chicken
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
manufacturer/tradename
Genway 15-288-22500
technique(s)
indirect ELISA: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... IL17A(3605)
General description
Interleukin-17a (IL-17A) is a member of the six member pro-inflammatory cytokine family called IL-17. The members are designated from IL-17A to IL-17F. IL-17A is synthesized by TH17 cells belonging to the CD4+ and CD8+ lineage. This gene is localized to human chromosome 6p12.1.
Application
Anti-Interleukin-17a antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
Interleukin-17A is a proinflammatory cytokine produced mainly by CD4+ T-lymphocytes and plays a critical role in inflammation. Chronic inflammation is a pathological feature of cancer. It may play an important role in tumor cell growth and progression. IL-17 levels might be useful for diagnostic and prognostic test for lung cancer patients with malignant pleural effusion (MPE). Cells producing IL-17 may act as a useful biomarker for the prognosis of sarcoidosis and play a role in the spontaneous recovery typical of patients with Löfgren′s syndrome.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Description
Pricing
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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S Sarkar et al.
Clinical and experimental immunology, 177(3), 652-661 (2014-05-13)
Interleukin (IL)-17 plays a critical role in inflammation. Most studies to date have elucidated the inflammatory role of IL-17A, often referred to as IL-17. IL-17F is a member of the IL-17 family bearing 50% homology to IL-17A and can also
Yin Duan et al.
Asian Pacific journal of cancer prevention : APJCP, 15(21), 9295-9300 (2014-11-26)
Interleukin-17A (IL-17A) is a multifunctional cytokine which plays a crucial role in the initiation and progression of cancer. To date, several studies have investigated associations between IL-17A -197G>A (rs2275913) polymorphism and digestive cancer risk, but the results remain conflicting. We
H Liang et al.
Scandinavian journal of immunology, 80(2), 144-150 (2014-05-13)
High-grade glioma is a malignant tumour; the pathogenesis is to be further investigated. Interleukin (IL)-17 is an inflammatory cytokine. Chronic inflammation is a pathological feature of cancer. This study aimed to characterize the glioma-derived IL-17(+) regulatory T cells (Treg). In
M Ostadkarampour et al.
Clinical and experimental immunology, 178(2), 342-352 (2014-06-26)
Sarcoidosis is a granulomatous disorder of unknown aetiology. The presence of Mycobacterium tuberculosis catalase-peroxidase (mKatG) in sarcoidosis tissue has been reported. T helper type 1 (Th1) responses against mKatG have previously been observed. However, little is known about interleukin (IL)-17 and
ChunHua Xu et al.
European journal of medical research, 19, 23-23 (2014-06-03)
Interleukin 17 (IL-17) is a proinflammatory cytokine produced mainly by CD4(+) T-lymphocytes and may be important in tumor cell growth and progression. In this study, we aimed to evaluate the diagnostic and prognostic value of pleural effusion levels of IL-17
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