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A9965

Sigma-Aldrich

N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-trifluoromethylcoumarin

≥95% (HPLC), powder

Synonym(s):

Ac-YVAD-AFC

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About This Item

Linear Formula:
C33H36N5O10F3
Molecular Weight:
719.66
MDL number:
MFCD01318881
UNSPSC Code:
12352209
PubChem Substance ID:
329771064
NACRES:
NA.32

Quality Level

200

Assay

≥95% (HPLC)

form

powder

color

white

storage temp.

−20°C

SMILES string

CC(C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccc3c(OC(=O)C=C3C(F)(F)F)c2

InChI

1S/C33H36F3N5O10/c1-15(2)28(41-31(49)23(38-17(4)42)11-18-5-8-20(43)9-6-18)32(50)37-16(3)29(47)40-24(14-26(44)45)30(48)39-19-7-10-21-22(33(34,35)36)13-27(46)51-25(21)12-19/h5-10,12-13,15-16,23-24,28,43H,11,14H2,1-4H3,(H,37,50)(H,38,42)(H,39,48)(H,40,47)(H,41,49)(H,44,45)/t16-,23-,24-,28-/m0/s1

InChI key

GWKJISJKNKIJNP-DEQDFGQZSA-N

Gene Information

human ... CASP1(834) , CASP4(837)
mouse ... CASP1(12362) , CASP4(12363)
rat ... CASP1(25166) , CASP4(114555)

Amino Acid Sequence

NAc-Tyr-Val-Ala-Asp-AFC

Substrates

Membrane-permeable fluorogenic substrate for caspase 1 (ICE) and caspase 4 (TX).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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