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A7544

Sigma-Aldrich

Anti-Albumin antibody produced in goat

whole antiserum

Synonym(s):

Serum albumin antibody

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About This Item

MDL number:
MFCD00162390
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

goat

Quality Level

200

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

15 mM sodium azide

species reactivity

human

technique(s)

indirect ELISA: 1:50,000
quantitative precipitin assay: 3.0

UniProt accession no.

P02768

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ALB(213)

General description

Albumin (ALB) is an autosomal gene with 15 exons mapped to human chromosome 4q13.3. The gene codes for a circulating human albumin protein containing 585 amino acid residues and 17 disulfide bridges. It is biosynthesized in the hepatocyte.

Immunogen

purified human albumin

Application

Anti-Albumin antibody produced in goat has been used in sandwich enzyme linked immunosorbent assays (ELISA), quantitative precipitin assay and immunofluorescence.

Biochem/physiol Actions

Albumin is a transport protein that binds a broad range of ligands such as fatty acids, bilirubin, hemin, drugs, amino acids and ions among several others. Albumin may also function as a zinc carrier protein and consequently regulate physiological processes.

Physical form

Supplied as a liquid containing 15mM sodium azide as preservative.

Preparation Note

treated to remove lipoproteins

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Maja Thim Larsen et al.
Journal of controlled release : official journal of the Controlled Release Society, 287, 132-141 (2018-07-18)
Recombinant albumin-drug genetic fusions are an effective technology to prolong the serum half-life of therapeutics that has resulted in marketed products. Indirect evidence suggests albumin fusions' long circulation is controlled by engagement with the cellular recycling neonatal Fc receptor (FcRn)
Albumin as fatty acid transporter
van der Vusse GJ
Drug Metabolism and Pharmacokinetics, 24, 300-307 (2009)
A novel mutation in the albumin gene (c.1A>C) resulting in analbuminemia
Caridi G, et al.
European Journal of Clinical Investigation, 43, 72-78 (2013)
Canstatin Gene Electrotransfer Combined With Radiotherapy: Preclinical Trials For Cancer Treatment.
Magnon, C., et al.
Gene, 15, 1436-1445 (2008)
Lucas Restrepo et al.
Annals of neurology, 70(2), 286-295 (2011-08-09)
Accurate assessment of Alzheimer's disease (AD), both presymptomatically and at different disease stages, will become increasingly important with the expanding elderly population. There are a number of indications that the immune system is engaged in AD. Here we explore the
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