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Key Documents

83870

Sigma-Aldrich

D-Ribose 5-phosphate barium salt hexahydrate

≥99.0% (TLC)

Synonym(s):

R-5-P-Ba

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About This Item

Empirical Formula (Hill Notation):
C5H9BaO8P · 6H2O
CAS Number:
Molecular Weight:
473.51
Beilstein:
3781061
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

≥99.0% (TLC)

form

powder

optical activity

[α]20/D +12±2°, c = 1% in 0.2 M HCl

storage temp.

2-8°C

SMILES string

[Ba++].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]C(=O)[C@H](O)[C@H](O)[C@H](O)COP([O-])([O-])=O

InChI

1S/C5H11O8P.Ba.6H2O/c6-1-3(7)5(9)4(8)2-13-14(10,11)12;;;;;;;/h1,3-5,7-9H,2H2,(H2,10,11,12);;6*1H2/q;+2;;;;;;/p-2/t3-,4+,5-;;;;;;;/m0......./s1

InChI key

WUZJSCGFQURQNK-BJLVBTRRSA-L

Application

D-Ribose 5-phosphate is used as a substrate to identify, differentiate and characterize ribose-5-phosphate isomerase(s) and phosphopentomutase(s). Ribose 5-phosphate is used to study the processes and effects of glycation in vivo and in vitro.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Claudia Vanesa Piattoni et al.
Plant physiology, 156(3), 1337-1350 (2011-05-07)
Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase (np-Ga3PDHase) is a cytosolic unconventional glycolytic enzyme of plant cells regulated by phosphorylation in heterotrophic tissues. After interaction with 14-3-3 proteins, the phosphorylated enzyme becomes less active and more sensitive to regulation by adenylates and inorganic pyrophosphate.
Maia M Cherney et al.
Journal of molecular biology, 413(4), 844-856 (2011-10-04)
Phosphoribosyl pyrophosphate (PRPP) synthetase catalyzes the transfer of the pyrophosphate group from ATP to ribose-5-phosphate (R5P) yielding PRPP and AMP. PRPP is an essential metabolite that plays a central role in cellular metabolism. The enzyme from a thermophilic archaeon Thermoplasma
Terhi Oja et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(16), 6024-6029 (2012-04-05)
Carbohydrate moieties are important components of natural products, which are often imperative for the solubility and biological activity of the compounds. The aromatic polyketide alnumycin A contains an extraordinary sugar-like 4'-hydroxy-5'-hydroxymethyl-2',7'-dioxane moiety attached via a carbon-carbon bond to the aglycone.
Mark J Koenigsknecht et al.
Microbiology (Reading, England), 156(Pt 3), 950-959 (2009-12-05)
Phosphoribosylamine (PRA) is the first intermediate in the common purine/thiamine biosynthetic pathway and is primarily synthesized by the product of the purF gene, glutamine phosphoribosylpyrophosphate (PRPP) amidotransferase (E.C. 2.4.2.14). Past genetic and biochemical studies have shown that multiple mechanisms for
Sabine A Stoffel et al.
Molecular and biochemical parasitology, 179(1), 1-7 (2011-05-17)
A single copy gene, encoding a protein highly similar to transketolase from other systems, was identified in the Trypanosoma brucei genome. The gene was expressed in E. coli and the purified protein demonstrated transketolase activity with K(m) values of 0.2mM

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