PHR8952

Mirtazapine

certified reference material, pharmaceutical secondary standard

• Synonym(s): Mirtazapine, 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
• Empirical Formula (Hill Notation): C₁₇H₁₉N₃
• CAS Number: 85650-52-8
• Molecular Weight: 265.35
• MDL number: MFCD00865427

Properties

• grade: certified reference material; pharmaceutical secondary standard
• CofA: current certificate can be downloaded
• packaging: pkg of 500 mg
• application(s): pharmaceutical
• storage temp.: -10 to -25°C
• SMILES string: CN1CCN2C(C1)c3ccccc3Cc4cccnc24
• InChI: 1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3
• InChI key: RONZAEMNMFQXRA-UHFFFAOYSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Biochem/physiol Actions

Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). Mirtazapine agonizes selective adrenergic and serotonergic receptors so that both NE release and 5-HT_1A mediated serotonergic signaling are increased.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.