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B0760

Supelco

Bufexamac

analytical standard

Synonym(s):

2-(p-Butoxyphenyl)acetohydroxamic acid

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About This Item

Empirical Formula (Hill Notation):
C12H17NO3
CAS Number:
2438-72-4
Molecular Weight:
223.27
EC Number:
219-451-1
MDL number:
MFCD00078936
UNSPSC Code:
41116107
PubChem Substance ID:
329773128
NACRES:
NA.24

grade

analytical standard

Quality Level

100

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CCCCOc1ccc(CC(=O)NO)cc1

InChI

1S/C12H17NO3/c1-2-3-8-16-11-6-4-10(5-7-11)9-12(14)13-15/h4-7,15H,2-3,8-9H2,1H3,(H,13,14)

InChI key

MXJWRABVEGLYDG-UHFFFAOYSA-N

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General description

Bufexamac is a drug with antipyretic, analgesic and anti-inflammatory properties.

Application

Bufexamac may be used as a reference standard in the determination of bufexamac in pharmaceutical formulations using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBW0026
011M1532V
011M1532
079K1789
017K1557

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P H Marttinen et al.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine, 53(6), 311-318 (2006-08-12)
The objective here was to evaluate the acute effects of induced arthritis on synovial fluid (SF) levels of matrix metalloproteinases (MMP) -2, -8 and -9 in horses. To evaluate MMP-2 and -9 activities and the effect of non-steroidal anti-inflammatory drug
Ritu Gupta et al.
The Australasian journal of dermatology, 47(2), 117-119 (2006-04-28)
A 24-year-old woman had a 9-week history of second to third daily urticaria that began after an episode of contact urticaria to topical bufexamac. She was found to have an underlying gastrointestinal infection with Blastocystis hominis. This was thought to
K Waltermann et al.
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 60(5), 424-427 (2008-12-19)
We report on a case of a bufexamac-induced allergic contact dermatitis with hematogenous dissemination presenting with the clinical and histological picture of a pigmented purpuric eruption. To our knowledge this is the first report on a bufexamac-induced pigmented purpuric dermatosis.
Hagen Trommer et al.
The Journal of pharmacy and pharmacology, 55(10), 1379-1388 (2003-11-11)
The effect of bufexamac on UV-irradiation-induced lipid peroxidation was investigated. Linolenic acid was used as a model lipid. Bufexamac was shown to be capable of reducing the amount of lipid peroxidation. The quantification was carried out by the thiobarbituric acid
Contact sensitivity to bufexamac.
Lachapelle JM.
Contact Dermatitis, 1(4), 261-261 (1975)
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