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35405

Supelco

α-Zearalanol solution

~10 μg/mL in acetonitrile, analytical standard

Synonym(s):

(3S,7R)-3,4,5,6,7,8,9,10,11,12-Decahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one solution, 2,4-Dihydroxy-6-(6α,10-dihydroxyundecyl)benzoic acid μ-lactone solution

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About This Item

Empirical Formula (Hill Notation):
C18H26O5
CAS Number:
26538-44-3
Molecular Weight:
322.40
EC Number:
200-835-2
MDL number:
MFCD00864182
UNSPSC Code:
85151701
PubChem Substance ID:
329755162

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

availability

not available in Canada

concentration

~10 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

SMILES string

C[C@H]1CCC[C@H](O)CCCCCc2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14+/m0/s1

InChI key

DWTTZBARDOXEAM-GXTWGEPZSA-N

General description

α-Zearalanol is a resorcyclic acid lactone. It is a plant derived, nonsteroidal phytoestrogen, often used as a dietary supplement.

Application

α-Zearalanol may be used as an analytical reference standard for the determination of the analyte in traditional Chinese medicines, human and animal urine by various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Analysis Note

purity : ≥97.0% (HPLC)

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2.0 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH2931
BCCF0197
BCCB8524
BCCB1173
BCBZ4520

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A rapid method for simultaneous determination of zearalenone, α-zearalenol, β-zearalenol, zearalanone, α-zearalanol and β-zearalanol in traditional Chinese medicines by ultra-high-performance liquid chromatography-tandem mass spectrometry.
Han Z, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 879(5-6), 411-420 (2011)
Shaohui Zong et al.
Journal of bone and mineral metabolism, 30(2), 136-143 (2011-07-21)
To assess the ability of α-zearalanol (α-ZAL) to prevent bone loss in an ovariectomized (OVX) rat model of osteoporosis, α-ZAL was administered intragastrically to rats. After 35 days, the total body bone mineral density (BMD) was assessed in all rats. All
Marcella L Card et al.
Journal of agricultural and food chemistry, 60(6), 1480-1487 (2012-01-10)
Surface runoff from manure-fertilized fields is a significant source of endocrine-disrupting compounds (EDCs) in the environment. Sorption by soils may play a major role in the environmental fate of manure-borne EDCs, including 17α- and 17β-estradiol (17α-E2 and 17β-E2), estrone (E1)
Shen Qu et al.
Environmental science & technology, 46(24), 13202-13211 (2012-11-21)
Trenbolone acetate, melengestrol acetate, and zeranol are synthetic hormones extensively used as growth promoters in animal agriculture, yet despite occurrence in water and soil little is known about their environmental fate. Here, we establish the time scales and mechanisms by
A Pazaiti et al.
International journal of clinical practice, 66(1), 28-36 (2011-12-08)
Zearalenone (ZEN) is a non-steroidal mycoestrogen that widely contaminates agricultural products. ZEN and its derivatives share similar molecular mechanisms and activity with estrogens and interact with ERα and ERβ leading to changes in the reproductive system in both animals and
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