03738

5-Fluorouracil

analytical standard

• Synonym(s): 2,4-Dihydroxy-5-fluoropyrimidine, 5-FU, 5-Fluoro-2,4(1H,3H)-pyrimidinedione
• Empirical Formula (Hill Notation): C₄H₃FN₂O₂
• CAS Number: 51-21-8
• Molecular Weight: 130.08
• Beilstein: 127172
• EC Number: 200-085-6
• MDL number: MFCD00006018
• UNSPSC Code: 41116107
• PubChem Substance ID: 329747789
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• Assay: ≥99.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• impurities: ≤0.5% water
• mp: 282-286 °C (dec.) (lit.)
• application(s): cleaning products; cosmetics; food and beverages; forensics and toxicology; personal care; pharmaceutical (small molecule)
• format: neat
• SMILES string: FC1=CNC(=O)NC1=O
• InChI: 1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
• InChI key: GHASVSINZRGABV-UHFFFAOYSA-N
• Gene Information: human ... TYMS(7298)

Description

General description

5-Fluorouracil is an anti-tumor agent, widely used in the treatment of various malignancies.

Application

5-Fluorouracil may be used as an analytical standard for the determination of the analyte in hospital effluents by capillary electrophoresis, and in biological samples and environmental samples by chromatography based techniques.

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H301,H351
• Precautionary Statements: P202 - P264 - P280 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 2
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3