Skip to Content
Merck
All Photos(1)

Key Documents

MABN18

Sigma-Aldrich

Anti-PINK1 Antibody, clone N4/49

clone N4/49, from mouse

Synonym(s):

PTEN induced putative kinase 1, protein kinase BRPK, serine/threonine-protein kinase PINK1, PTEN-induced putative kinase protein 1, Parkinson disease (autosomal recessive) 6

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

N4/49, monoclonal

species reactivity

human

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG1κ

NCBI accession no.

NP_115785

UniProt accession no.

Q9BXM7

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... PINK1(65018)

General description

Mutations in the PTEN-induced kinase 1 (PINK1) gene located within the PARK6 locus on chromosome 1p35-p36 have recently been identified in patients with recessive early-onset Parkinson disease. Data suggests that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance.

Specificity

This antibody recognizes PINK1.

Application

This Anti-PINK1 Antibody, clone N4/49 is validated for use in IH, WB for the detection of PINK1.
Western Blot Analysis: A previous lot of MABN18 recognized PINK1 in HEK cells and a rat brain LSP, as reported by an independent laboratory (UC Davis/NIH NeuroMab Facility; www.neuromab.org/neuromab@ucdavis.edu).

Quality

Evaluated by Immunohistochemistry in human normal brain tissue.

Immunohistochemistry Analysis: A 1:500 dilution of this antibody detected PINK1 in human normal brain tissue.

Target description

63 kDa Observed

Physical form

Format: Purified

Analysis Note

Control
Human normal brain tissue

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service