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A-916

Supelco

7-Aminoclonazepam solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C15H12ClN3O
CAS Number:
4959-17-5
Molecular Weight:
285.73
MDL number:
MFCD00798467
UNSPSC Code:
41116107
PubChem Substance ID:
329771039
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

2-8°C

SMILES string

NC1=CC=C2C(C(C3=C(Cl)C=CC=C3)=NCC(N2)=O)=C1

InChI

1S/C15H12ClN3O/c16-12-4-2-1-3-10(12)15-11-7-9(17)5-6-13(11)19-14(20)8-18-15/h1-7H,8,17H2,(H,19,20)

InChI key

HEFRPWRJTGLSSV-UHFFFAOYSA-N

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General description

This certified Snap-N-Spike® solution is suitable for use as a starting material in calibrators and controls for numerous GC/MS or LC/MS applications in forensic analysis, clinical toxicology and urine drug testing. As a major metabolite, 7-aminoclonazepam may be used to monitor use of the parent drug, clonazepam. Clonazepam, marketed as Klonopin® and Rivotril, is a long-acting benzodiazepine with anxiolytic, anticonvulsant, muscle relaxant, and hypnotic properties.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Klonopin is a registered trademark of Hoffmann-La Roche Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

A-915

7-Aminoclonazepam solution, 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

A-917

7-Aminoclonazepam-d4 solution, 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

A-924

7-Aminoclonazepam-d4 solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

B-033

Benzodiazepine Multi-component Mixture-8 solution, 250 μg/mL each component in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

B-905

Benzodiazepine Internal Standard-3 solution, 0.5-1.0 mg/mL in acetonitrile, ampule of 1.0 mL, certified reference material, Cerilliant®

C-905

Clonazepam-d4 solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

C-906

Clonazepam-d4 solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

C-907

Clonazepam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

F-047

Flubromazolam solution, 1.0 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

D-159

Diclazepam solution, 1 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

M-197

Meclonazepam solution, 1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

M-198

Meclonazepam-D3 solution, 100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

D-160

Diclazepam-D4 solution, 100 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup

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Adam Negrusz et al.
Journal of analytical toxicology, 26(7), 471-478 (2002-11-09)
The objective of this paper was to determine whether benzodiazepine clonazepam (CLO) and its major metabolite 7-aminoclonazepam (7-ACLO) could be detected in hair collected from healthy volunteers after receiving a single 3-mg dose of Klonopin (clonazepam). Such data would be
Adam Negrusz et al.
Analytical and bioanalytical chemistry, 376(8), 1198-1204 (2003-07-08)
The objective of this paper was to determine how long after administration of benzodiazepine clonazepam (CLO), its major metabolite 7-aminoclonazepam (7-ACLO) could be detected in urine collected from 10 healthy volunteers who received a single 3-mg dose of Klonopin (clonazepam).
I Petters et al.
Journal of chromatography, 306, 241-248 (1984-03-09)
A high-performance liquid chromatographic method is reported for the determination of clonazepam and its metabolites 7-amino- and 7-acetamidoclonazepam. Extraction from buffered plasma is carried out at pH 9.5 with hexane-ethyl acetate (7:3) for clonazepam and with chloroform for the metabolites.
Albert A Elian
Forensic science international, 134(1), 54-56 (2003-07-05)
The ability of five commercially available enzyme-linked immunosorbent assay (ELISA) benzodiazepines to detect clonazepam and 7-aminoclonazepam in blood and urine was investigated. To determine the cross-reactivity of various ELISA assays, drug free blood and urine were fortified with clonazepam and
Marjorie Chèze et al.
Forensic science international, 145(2-3), 123-130 (2004-09-29)
The number of reports on drug facilitated crimes is increasing these last years. Apart from ethanol and cannabis, benzodiazepines (BZD) and analogs are the most common drugs reported to be used probably due to their amnesic and sedative properties. We
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Global Trade Item Number

SKUGTIN
669997-100MG4061833554791
669997-500MG4061833554807
700174P-5MG4061838472427
OP181-100UG
Z720771-75EA4061834388296
Z720798-20EA4061832967301
D7039-1CS4061834374145
D6315-1CS4061834379935
D6440-1CS4061834379942
D6789-1CS4061826744420
Z687162-100EA4061832967011
H9649-1MG4061826675267
C3920-5MG4061832628707
C4045-5MG
C4045-10MG
Z688657-450EA4061832967028
F8667-1CS4061834374350
F8542-1CS4061826744710
D8440-100UG4061838070760
TMO1329204061841580317
Z720860-10EA4061832967356
Z720895-6EA
F7552-1CS4061826744673
F7677-1CS4061826744680
F7302-1CS4061834379997

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