850370P
Avanti
21:0 PC
1,2-diheneicosanoyl-sn-glycero-3-phosphocholine, powder
Synonym(s):
PC(21:0/21:0)
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About This Item
Empirical Formula (Hill Notation):
C50H100NO8P
CAS Number:
Molecular Weight:
874.30
UNSPSC Code:
51191904
NACRES:
NA.25
Recommended Products
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 200 mg (850370P-200mg)
pkg of 1 × 25 mg (850370P-25mg)
manufacturer/tradename
Avanti Polar Lipids 850370P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCCCCC)=O)=O
General description
Phosphatidylcholines (PCs) are phospholipids, that are ubiquitously present in the tissues of animals. The sn-1 and sn-2 position of PC has saturated and unsaturated fatty acids respectively. It can be produced through methylation pathway.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
Application
21:0 PC has been used as a standard in linearity experiment to evaluate linearity response of the most abundant lipid classes. 21:0 PC may be used as an internal standard for the quantification of phospholipids (PLs). It may also be used as a phospholipid standard for the analysis of dried lipid extracts of S. meliloti in the positive-ionization mode.
Biochem/physiol Actions
Phosphatidylcholine (PC) helps to block the penetrance of bacteria by acting as a surfactant in the mucus.
Packaging
5 mL Amber Glass Screw Cap Vial (850370P-200mg)
5 mL Amber Glass Screw Cap Vial (850370P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Lipids II: Phospholipids, Glycosphingolipids, and Cholesterol
Essentials of Medical Biochemistry, 299-320 (2015)
Libia Saborido Basconcillo et al.
Journal of lipid research, 50(6), 1120-1132 (2008-12-20)
A shotgun lipidomics approach that allowed the analysis of eight lipid classes directly from crude extracts of the soil bacterium Sinorhizobium meliloti is presented. New MS-MS transitions are reported for the analysis of monomethylphosphatidylethanolamines, dimethylphosphatidylethanolamines, and three bacterial non-phosphorus-containing lipid
Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
Frauke Mücksch et al.
Scientific reports, 9(1), 17661-17661 (2019-11-30)
Human immunodeficiency virus type 1 (HIV-1) acquires its lipid envelope during budding from the plasma membrane of the host cell. Various studies indicated that HIV-1 membranes differ from producer cell plasma membranes, suggesting budding from specialized membrane microdomains. The phosphoinositide
Mathias Haag et al.
Metabolites, 2(1), 57-76 (2012-01-01)
Lipids, such as phosphoinositides (PIPs) and diacylglycerol (DAG), are important signaling intermediates involved in cellular processes such as T cell receptor (TCR)-mediated signal transduction. Here we report identification and quantification of PIP, PIP2 and DAG from crude lipid extracts. Capitalizing
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