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700122P

Avanti

campestanol

Avanti Research™ - A Croda Brand 700122P, powder

Synonym(s):

5α-campestan-3β-ol

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About This Item

Empirical Formula (Hill Notation):
C28H50O
CAS Number:
474-60-2
Molecular Weight:
402.70
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700122P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 700122P

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C28H50O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h18-26,29H,7-17H2,1-6H3/t19-,20-,21+,22+,23+,24-,25+,26+,27+,28-/m1/s1

InChI key

ARYTXMNEANMLMU-ATEDBJNTSA-N

General description

Campestanol has a methyl group at the C-24. It comprises the 10-30% of stanol content in vegetable oil. It is naturally occurring and has similar structure as cholesterol. Campestanol is synthesized by the hydrogenation of campesterol.
Campestanol is a saturated plant stanol.

Biochem/physiol Actions

Campestanol absorption in intestine is similar to that of cholesterol absorption pathway. However, in sitosterolemic homozygotes, it is hyperabsorbed from the intestine.
Intestinal absorption of campestanol is lesser compared to cholesterol due to the presence of side chain. Due to the structural similarity with cholesterol, campestanol reduces cholesterol absorption in the intestine and the plasma level of LDL cholesterol.

Packaging

5 mL Amber Glass Screw Cap Vial (700122P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Brassinosteroid deficiency due to truncated steroid 5alpha-reductase causes dwarfism in the lk mutant of pea
Nomura , et al.
Plant Physiology, 135(4), 2220-2229 (2004)
SOFW Journal, 149-149 (2002)
Campestanol (24-methyl-5alpha-cholestan-3beta-ol) absorption and distribution in New Zealand white rabbits: effect of dietary sitostanol
Xu G, et al.
Metabolism, Clinical and Experimental, 48(3), 363-368 (1999)
Hyperabsorption and retention of campestanol in a sitosterolemic homozygote: comparison with her mother and three control subjects
Salen, Gerald and Xu, Guorong and Tint, GS and Batta, AK and Shefer, Sarah
Journal of Lipid Research, 41(11), 1883-1889 (2000)
Campestanol (24-methyl-5alpha-cholestan-beta-ol) absorption and distribution in New Zealand white rabbits: effect of dietary sitostanol
Xu G, et al.
Metabolism and Disease, 48(3), 363-368 (1999)
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