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852279

Sigma-Aldrich

2′-Deoxyinosine

99%

Synonym(s):

9-(2-Deoxy-β-D-ribofuranosyl)hypoxanthine

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About This Item

Empirical Formula (Hill Notation):
C10H12N4O4
CAS Number:
Molecular Weight:
252.23
Beilstein:
33517
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:

Quality Level

Assay

99%

form

powder

SMILES string

OC[C@H]1O[C@H](C[C@@H]1O)n2cnc3C(=O)NC=Nc23

InChI

1S/C10H12N4O4/c15-2-6-5(16)1-7(18-6)14-4-13-8-9(14)11-3-12-10(8)17/h3-7,15-16H,1-2H2,(H,11,12,17)/t5-,6+,7+/m0/s1

InChI key

VGONTNSXDCQUGY-RRKCRQDMSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Rongjuan Mi et al.
    Mutation research, 735(1-2), 12-18 (2012-06-06)
    The human endonuclease V gene is located in chromosome 17q25.3 and encodes a 282 amino acid protein that shares about 30% sequence identity with bacterial endonuclease V. This study reports biochemical properties of human endonuclease V with respect to repair
    A Cohen et al.
    The New England journal of medicine, 295(26), 1449-1454 (1976-12-23)
    To delineate the normal function of purine nucleoside phosphorylase and to understand the pathogenesis of the immune dysfunction associated with deficiency of this enzyme, we studied purine metabolism in a patient deficient in purine nucleoside phosphorylase, her erythrocytes and cultured
    Norman E Watkins et al.
    Nucleic acids research, 33(19), 6258-6267 (2005-11-03)
    Nearest-neighbor thermodynamic parameters of the 'universal pairing base' deoxyinosine were determined for the pairs I.C, I.A, I.T, I.G and I.I adjacent to G.C and A.T pairs. Ultraviolet absorbance melting curves were measured and non-linear regression performed on 84 oligonucleotide duplexes
    Manabu Yasui et al.
    Journal of molecular biology, 377(4), 1015-1023 (2008-02-29)
    Chronic inflammation involving constant generation of nitric oxide (*NO) by macrophages has been recognized as a factor related to carcinogenesis. At the site of inflammation, nitrosatively deaminated DNA adducts such as 2'-deoxyinosine (dI) and 2'-deoxyxanthosine are primarily formed by *NO
    Bernard Weiss
    DNA repair, 7(2), 205-212 (2007-11-06)
    Deoxyinosine (dI) is produced in DNA by the hydrolytic or nitrosative deamination of deoxyadenosine. It is excised in a repair pathway that is initiated by endonuclease V, the product of the nfi gene. The repair was studied in vivo using

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