803898

Mattson Difluoroborate Urea

• Synonym(s): N-[3,5-bis(trifluoromethyl)phenyl]-N′-[2-(difluoroboryl)phenyl]-Urea
• Empirical Formula (Hill Notation): C₁₅H₉BF₈N₂O
• CAS Number: 1451048-80-8
• Molecular Weight: 396.04
• UNSPSC Code: 12352300
• PubChem Substance ID: 329768832
• NACRES: NA.22

Properties

• form: powder
• reaction suitability: reagent type: catalyst
• greener alternative product characteristics: Catalysis; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• mp: 223-228 °C
• greener alternative category: Aligned,
• storage temp.: 2-8°C
• SMILES string: O=C(NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)NC2=CC=CC=C2B(F)F
• InChI: 1S/C15H9BF8N2O/c17-14(18,19)8-5-9(15(20,21)22)7-10(6-8)25-13(27)26-12-4-2-1-3-11(12)16(23)24/h1-7H,(H2,25,26,27)
• InChI key: VTRJGINZAJTRDQ-UHFFFAOYSA-N

Description

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information.

Application

1-(3,5-bis(trifluoromethyl)phenyl)-3-(2-(difluoroboryl)phenyl)urea is a robust and user-friendly white solid capable of being stored on the benchtop indefinitely. The strategic incoporation of the difluoroboryl substituent renders this the most acidic urea catalyst reported to date (pKa(DMSO) = 7.5). This difluorboronate urea benefits from enhanced reaction rates and yields when compared to traditional urea catalysts. It also enables reactions that are inaccessible with conventional urea catalysis.

Other Notes

Arylation of Diazoesters by a Transient N-H Insertion Organocascade

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable