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704334

Sigma-Aldrich

2-Ketoglutaric acid-1-13C

99 atom % 13C, 95% (CP)

Synonym(s):

α-Ketoglutaric acid-1-13C, 2-Ketopentanedioic acid-1-13C, 2-Oxoglutaric acid-1-13C, 2-Oxopentanedioic acid-1-13C

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About This Item

Linear Formula:
HOCOCH2CH2CO13CO2H
CAS Number:
Molecular Weight:
147.09
MDL number:
UNSPSC Code:
12352115
PubChem Substance ID:

isotopic purity

99 atom % 13C

Assay

95% (CP)

form

solid

technique(s)

bio NMR: suitable

mp

114-117 °C

mass shift

M+1

storage temp.

2-8°C

SMILES string

OC(=O)CCC(=O)[13C](O)=O

InChI

1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)/i5+1

InChI key

KPGXRSRHYNQIFN-HOSYLAQJSA-N

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Articles

We present an article about the hyperpolarization of 13C labeled metabolites, especially pyruvic acid, using dynamic nuclear polarization (DNP) that allows real-time magnetic resonance spectroscopy.

Sigma-Aldrich.com presents an article concerning MRI/MRS and the use of isotopes in hyperpolarization.

Dynamic Nuclear Polarization (DNP) is a phenomenon by which high spin polarization, typically derived from a bath of free radical electrons, is transferred to a nuclear spin bath, enhancing the difference between the nuclear energy levels and thereby producing dramatically enhanced NMR signals for detection.

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