655864

5-(Aminomethyl)indole

95%

• Synonym(s): Indole-5-methanamine
• Empirical Formula (Hill Notation): C₉H₁₀N₂
• CAS Number: 81881-74-5
• Molecular Weight: 146.19
• MDL number: MFCD01719220
• UNSPSC Code: 12352100
• PubChem Substance ID: 24884128
• NACRES: NA.22

Properties

• Assay: 95%
• form: solid
• mp: 114-122 °C
• functional group: amine
• SMILES string: NCc1ccc2[nH]ccc2c1
• InChI: 1S/C9H10N2/c10-6-7-1-2-9-8(5-7)3-4-11-9/h1-5,11H,6,10H2
• InChI key: UAYYSAPJTRVEQA-UHFFFAOYSA-N

Description

Application

Reactant for preparation of:

• HIV-1 integrase inhibitors targeting the catalytic domain and its ability for interaction with LEDGF/p75
• Inhibitors of Gli1-mediated transcription in the Hedgehog pathway
• SCIO-469-like compounds for the inhibition of p38 MAP kinase
• 4-(indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitriles as protein kinase c theta (PKC θ) inhibitors
• Non-covalent thrombin inhibitors

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves