60034

4-Aminophenol

≥99% (HPLC)

• Synonym(s): 4-Hydroxyaniline
• Linear Formula: H₂NC₆H₄OH
• CAS Number: 123-30-8
• Molecular Weight: 109.13
• Beilstein: 385836
• EC Number: 204-616-2
• MDL number: MFCD00007869
• UNSPSC Code: 12352100
• PubChem Substance ID: 57651713

Properties

• Assay: ≥99% (HPLC)
• form: powder
• mp: 185-189 °C (lit.); 186-188 °C
• solubility: water: slightly soluble
• SMILES string: Nc1ccc(O)cc1
• InChI: 1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2
• InChI key: PLIKAWJENQZMHA-UHFFFAOYSA-N

Description

General description

4-Aminophenol is an organic building block. Its voltammetric estimation in water samples by employing single-wall carbon nanotubes (SWNT)-Nafion film coated glassy carbon electrode has been reported. It is present as the main contaminant in the pharmaceutical formulation of paracetamol. Its quantification in multicomponent dosage preparations of paracetamol by HPLC coupled with amperometric detection has been described.

Application

4-Aminophenol may be used in the synthesis of 2,2-bis(4-aminophenoxy) benzonitrile [4-APBN], a monomer required for the preparation of series of polyamides and poly(amide-imide)s. It may be used as derivatization reagent during paper spray ionization mass spectrometric estimation of aldehydes.

Safety Information

• Pictograms: GHS08,GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H302 + H332,H317,H341,H373,H410
• Precautionary Statements: P273 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2 - Skin Sens. 1 - STOT RE 2
• Target Organs: Kidney
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves