495212

4-Hydroxy-3-nitropyridine

98%

• Synonym(s): 3-Nitro-4-pyridinol
• Empirical Formula (Hill Notation): C₅H₄N₂O₃
• CAS Number: 5435-54-1
• Molecular Weight: 140.10
• MDL number: MFCD00128874
• UNSPSC Code: 12352100
• PubChem Substance ID: 329757469
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 98%
• mp: 285 °C (dec.) (lit.)
• functional group: nitro
• SMILES string: Oc1ccncc1[N+]([O-])=O
• InChI: 1S/C5H4N2O3/c8-5-1-2-6-3-4(5)7(9)10/h1-3H,(H,6,8)
• InChI key: YUWOLBZMQDGRFV-UHFFFAOYSA-N

Description

General description

4-Hydroxy-3-nitropyridine can be synthesized by the nitration of 4-hydroxypyridine.

Application

4-Hydroxy-3-nitropyridine may be used in the synthesis of 4-ethoxy-3-nitropyridine by treating with phosphorus pentachloride (PCl₅) followed by ethanol. It may also be used to prepare 4-chloro-3-nitropyridine by treating with PCl₅-POCl₃ (phosphorus oxychloride).

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves