481181
Silver(I) sulfadiazine
98%
Synonym(s):
Silver sulfadiazine, Sulfadiazine silver
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About This Item
Empirical Formula (Hill Notation):
C10H9AgN4O2S
CAS Number:
Molecular Weight:
357.14
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.23
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Quality Level
Assay
98%
form
powder
mp
285 °C (dec.) (lit.)
SMILES string
Nc1ccc(cc1)S(=O)(=O)N([Ag])c2ncccn2
InChI
1S/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1
InChI key
UEJSSZHHYBHCEL-UHFFFAOYSA-N
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Application
Silver(I) sulfadiazine (AgSD) is popularly used for treating second-degree burn wounds as it acts as an antimicrobial agent and prevents infections. Silver sulfadiazine-impregnated polyurethane (PU) foam, chitosan/chondroitin sulfate films may be used for wound dressing.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
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Jason Wasiak et al.
The Cochrane database of systematic reviews, 3(3), CD002106-CD002106 (2013-04-02)
An acute burn wound is a complex and evolving injury. Extensive burns produce systemic consequences, in addition to local tissue damage. Treatment of partial thickness burn wounds is directed towards promoting healing and a wide variety of dressings are currently
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Journal of burn care & research : official publication of the American Burn Association, 33(6), e309-e312 (2012-11-13)
As a superstition, homemade decoctions are believed to be beneficial for several diseases. This kind of medical therapy, however, can lead to serious adverse effects. In this report, we present three cases from a single family. Each of the family
Silver sulfadiazine-a new topical therapy for pseudomonas in burns: therapy of pseudomonas infection in burns
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Archives of Surgery (Chicago, Ill. : 1960), 96(2), 184-188 (1968)
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International wound journal, 9 Suppl 2, 1-19 (2013-01-05)
The TIME acronym (tissue, infection/inflammation, moisture balance and edge of wound) was first developed more than 10 years ago, by an international group of wound healing experts, to provide a framework for a structured approach to wound bed preparation; a
Meenakshi Venkataraman et al.
AAPS PharmSciTech, 14(1), 254-264 (2013-01-01)
The objective of the present study was to formulate stable silver sulfadiazine (SSD) nanosuspensions and nanogels suitable for topical delivery with a view to increase bactericidal activity in burn therapy. SSD nanosuspensions were formulated using the microprecipitation-high-pressure homogenization technique. An
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