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47319

Sigma-Aldrich

Fmoc-D-Tyr(tBu)-OH

≥98.0% (HPLC)

Synonym(s):

Fmoc-O-tert-butyl-D-tyrosine

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About This Item

Empirical Formula (Hill Notation):
C28H29NO5
CAS Number:
118488-18-9
Molecular Weight:
459.53
Beilstein:
6691868
MDL number:
MFCD00065684
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
57650924
NACRES:
NA.26

Assay

≥98.0% (HPLC)

form

solid

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

CC(C)(C)Oc1ccc(C[C@@H](NC(=O)OCC2c3ccccc3-c4ccccc24)C(O)=O)cc1

InChI

1S/C28H29NO5/c1-28(2,3)34-19-14-12-18(13-15-19)16-25(26(30)31)29-27(32)33-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,29,32)(H,30,31)/t25-/m1/s1

InChI key

JAUKCFULLJFBFN-RUZDIDTESA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Kazuma Ogawa et al.
Chemical & pharmaceutical bulletin, 66(6), 651-659 (2018-06-05)
Radiolabeled cyclic peptides containing the (Arg-Gly-Asp) RGD sequence for use in positron emission tomography (PET) imaging, single-photon emission computed tomography (SPECT) imaging, and targeted radionuclide therapy of cancer have been reported. In this study, RGD was used as a model
Fayçal Touti et al.
Nature chemical biology, 15(4), 410-418 (2019-03-20)
The use of competitive inhibitors to disrupt protein-protein interactions (PPIs) holds great promise for the treatment of disease. However, the discovery of high-affinity inhibitors can be a challenge. Here we report a platform for improving the affinity of peptide-based PPI
Andreas Pech et al.
Nucleic acids research, 45(7), 3997-4005 (2017-02-06)
Biological evolution resulted in a homochiral world in which nucleic acids consist exclusively of d-nucleotides and proteins made by ribosomal translation of l-amino acids. From the perspective of synthetic biology, however, particularly anabolic enzymes that could build the mirror-image counterparts

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