409537

Poly(ethylene glycol) methacrylate

average M_n 360, methacrylate, 500-800 ppm MEHQ as inhibitor

• Synonym(s): Ethoxylated 2-hydroxyethyl methacrylate, PEGMA, Poly(ethylene oxide) monomethacrylate, Polyethylene glycol
• Linear Formula: H₂C=C(CH₃)CO(OCH₂CH₂)_nOH
• CAS Number: 25736-86-1
• MDL number: MFCD00081879
• UNSPSC Code: 12162002
• NACRES: NA.23

Properties

• product name: Poly(ethylene glycol) methacrylate, average M_n 360, contains 500-800 ppm MEHQ as inhibitor
• form: liquid
• mol wt: average M_n 360
• contains: 500-800 ppm MEHQ as inhibitor
• reaction suitability: reagent type: cross-linking reagent; reaction type: Polymerization Reactions
• refractive index: n20/D 1.464
• density: 1.105 g/mL at 25 °C
• Ω-end: hydroxyl
• α-end: methacrylate
• polymer architecture: shape: linear; functionality: heterobifunctional
• InChI: 1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3
• InChI key: WOBHKFSMXKNTIM-UHFFFAOYSA-N

Description

General description

Polyethylene glycol (PEG) is a suitable material for biological applications since it does not trigger an immune response. It can by synthesized by anionic ring opening polymerization of ethylene oxide with a range of end groups (such as methacrylate: PEGMA) attached. PEG is a hydrophilic polymer that can form hydrogels when cross linked into networks. Acrylate and methacrylate chain ends undergo chain polymerization to from PEGMA hydrogels.

Application

PEGMA can beused as a monomer to synthesize:

• Degradable microspheres using asuspension polymerization process. The amphiphilic nature of PEGMA allows performingthe polymerization by direct oil in the water suspension process.
• Polymeric chelating beads for the effectiveremoval of heavy metals from aqueous solutions.

It can also be used to synthesize micro or nanoparticles-basedchitosan /PEGMA composite by Michael addition reaction. The PEGMA graftingimproves the solubility of chitosan in aqueous media. These particles can beused as carriers in the ophthalmic drug delivery system.

Physical form

Monomethacrylate functionalized

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315
• Precautionary Statements: P264 - P280 - P302 + P352 - P332 + P313 - P362 + P364
• Hazard Classifications: Skin Irrit. 2
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves