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232505

Sigma-Aldrich

1,2-Dihydroxynaphthalene

technical grade

Synonym(s):

1,2-Naphthalenediol

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About This Item

Linear Formula:
C10H6(OH)2
CAS Number:
Molecular Weight:
160.17
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

grade

technical grade

mp

101-103 °C (lit.)

SMILES string

Oc1ccc2ccccc2c1O

InChI

1S/C10H8O2/c11-9-6-5-7-3-1-2-4-8(7)10(9)12/h1-6,11-12H

InChI key

NXPPAOGUKPJVDI-UHFFFAOYSA-N

General description

1,2-Dihydroxynaphthalene is the most sensitive biomarker for an internal exposure to naphthalene in humans.

Application

1,2-Dihydroxynaphthalene was used as substrate to investigate the rate of oxygen consumption by washed cell suspensions of Corynebacterium sp. strain C125 grown on o-xylene, tetralin or succinate.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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R W Eaton et al.
Journal of bacteriology, 174(23), 7542-7554 (1992-12-01)
The reactions involved in the bacterial metabolism of naphthalene to salicylate have been reinvestigated by using recombinant bacteria carrying genes cloned from plasmid NAH7. When intact cells of Pseudomonas aeruginosa PAO1 carrying DNA fragments encoding the first three enzymes of
Khalid A Ibrahim et al.
Pakistan journal of pharmaceutical sciences, 30(2(Suppl.)), 579-583 (2017-06-27)
Medicated jelly formulations are patient friendly dosage form for pediatric, geriatric and dysphagic patients. These formulations offer rapid dissolution and absorption of drugs through oral mucosa therefore show the early onset of action. The objective of the study was to
S Sato
Investigative ophthalmology & visual science, 34(11), 3172-3178 (1993-10-01)
Recent studies have indicated that certain aldose reductase inhibitors prevent the formation of cataracts in naphthalene-fed rats. The study was designed to investigate whether aldose reductase itself is involved in the metabolism of naphthalene in the lens and the mechanism
Huilan Fu et al.
Molecular plant pathology, 21(10), 1337-1352 (2020-08-11)
The basal transcription factor II H (TFIIH) is a multicomponent complex. In the present study, we characterized a TFIIH subunit Tfb5 by analysing loss- and gain-of-function mutants to gain a better understanding of the molecular mechanisms underlying stress resistance and
E Andújar et al.
Journal of bacteriology, 182(3), 789-795 (2000-01-14)
A genomic region involved in tetralin biodegradation was recently identified in Sphingomonas strain TFA. We have cloned and sequenced from this region a gene designated thnC, which codes for an extradiol dioxygenase required for tetralin utilization. Comparison to similar sequences

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