Skip to Content
Merck
All Photos(1)

Key Documents

More Documents

213187

Sigma-Aldrich

2-Methyl-5-nitroanisole

99%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
CH3C6H3(NO2)OCH3
CAS Number:
13120-77-9
Molecular Weight:
167.16
EC Number:
236-048-6
MDL number:
MFCD00043912
UNSPSC Code:
12352100
PubChem Substance ID:
24852771
NACRES:
NA.22

Assay

99%

mp

69-71 °C (lit.)

SMILES string

COc1cc(ccc1C)[N+]([O-])=O

InChI

1S/C8H9NO3/c1-6-3-4-7(9(10)11)5-8(6)12-2/h3-5H,1-2H3

InChI key

WVQGZNRUEVFXKR-UHFFFAOYSA-N

Application

2-Methyl-5-nitroanisole was used in the synthesis of:
  • 2-methoxy-p-toluidine via reduction with tin and hydrochloric acid
  • 2-methoxy-4-nitrobenzyl bromide

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Anodic oxidations. VII. Nuclear cyanation of methylanisoles.
Yoshida K, et al.
The Journal of Organic Chemistry, 40(1), 63-66 (1975)
P K Chakraborty et al.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 42(7), 673-681 (1991-01-01)
The synthesis of 4-[18F]fluoroguaiacol (4-[18F]fluoro-2-methoxyphenol) has been achieved in no-carrier-added form starting from 2-methoxy-4-nitrobenzaldehyde, using nucleophilic aromatic substitution by [18F]fluoride followed by Baeyer-Villiger oxidation of the benzaldehyde to the phenol. Demethylation with boron tribromide gave 4-[18F]fluorocatechol (1,2-dihydroxy-4-[18F]fluorobenzene) with an overall

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service