RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
Synonyms:
RIB1, RNS1
Species:
Human RNASE1 (6035), Mouse Rnase1 (19752), Rat Rnase1 (364304), naked mole-rat Rnase1 (101706346), cow RNASE1 (282340), sheep RNASE1 (101113761), cow RNASE1 (280930), fruit fly Rnase1 (5656971), dog RNASE1 (475395), domestic cat RNASE1 (101082663)
UniProtKB ID:
Gene ID:
- Human(6035) Summary: This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
- Mouse(19752) ribonuclease, RNase A family, 1 (pancreatic)
- Rat(364304) ribonuclease, RNase A family, 1 (pancreatic)
- naked mole-rat(101706346) ribonuclease, RNase A family, 1 (pancreatic)
- cow(282340) ribonuclease, RNase A family, 1 (pancreatic)
- sheep(101113761) ribonuclease, RNase A family, 1 (pancreatic)
- cow(280930) ribonuclease, RNase A family, 1 (pancreatic)
- fruit fly(5656971) Ribonuclease 1
- dog(475395) ribonuclease, RNase A family, 1 (pancreatic)
- domestic cat(101082663) ribonuclease, RNase A family, 1 (pancreatic)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RNASE1 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
western blot