1444279

Mirtazapine

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
• Empirical Formula (Hill Notation): C₁₇H₁₉N₃
• CAS Number: 85650-52-8
• Molecular Weight: 265.35
• MDL number: MFCD00865427
• UNSPSC Code: 41116107
• PubChem Substance ID: 329750473
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: mirtazapine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: CN1CCN2C(C1)c3ccccc3Cc4cccnc24
• InChI: 1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3
• InChI key: RONZAEMNMFQXRA-UHFFFAOYSA-N
• Gene Information: human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , HTR2A(3356) , HTR2C(3358)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Mirtazapine USP reference standard for use in specified quality tests and assays. 

Also used to prepare standard, standard stock, and system suitability solution for the assay and identification by using liquid chromatography coupled with UV detector according to the given below monographs of United States Pharmacopeia (USP): 

• Mirtazapine Orally Disintegrating Tablets
• Mirtazapine Compounded Oral Suspension, Veterinary
• Mirtazapine

Biochem/physiol Actions

Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). Mirtazapine agonizes selective adrenergic and serotonergic receptors so that both NE release and 5-HT_1A mediated serotonergic signaling are increased.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302 - H336
• Precautionary Statements: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable