1254508

Estriol

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 1,3,5(10)-Estratriene-3,16α,17β-triol, 16α-Hydroxyestradiol, 3,16α,17β-Trihydroxy-1,3,5(10)-estratriene
• Empirical Formula (Hill Notation): C₁₈H₂₄O₃
• CAS Number: 50-27-1
• Molecular Weight: 288.38
• Beilstein: 2508172
• MDL number: MFCD00003691
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749756
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: estriol
• manufacturer/tradename: USP
• mp: 280-282 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1C[C@@H](O)[C@@H]2O
• InChI: 1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1
• InChI key: PROQIPRRNZUXQM-ZXXIGWHRSA-N

Description

General description

Estriol is found to be a major estrogen in pregnant women. It originates in the placenta from the estrogen precursors, made by the fetal adrenal gland and liver. Estriol levels are directly related to the delivery of the fetus and serve as an index of the fetal well-being.

Application

Estriol may be used as a pharmaceutical primary standard for the quantification of the analyte in pharmaceutical formulations using chromatography techniques.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H351 - H360FD - H362
• Precautionary Statements: P202 - P260 - P263 - P264 - P280 - P308 + P313
• Hazard Classifications: Carc. 2 - Lact. - Repr. 1A
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3