SAB4700393
Monoclonal Anti-CD11c-PE antibody produced in mouse
clone BU15, purified immunoglobulin, buffered aqueous solution
Synonym(s):
Anti-ITGAX
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.44
Recommended Products
biological source
mouse
Quality Level
conjugate
phycoerythrin (R-PE) conjugate
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
BU15, monoclonal
form
buffered aqueous solution
species reactivity
monkey, canine, human
technique(s)
flow cytometry: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... ITGAX(3687)
General description
The antibody BU15 reacts with CD11c (alphaX, p150), a 150 kDa integrin expressed mainly on dendritic cells and tissue macrophages.
Immunogen
Dendritic cells of synovial fluid
Application
The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (2 mL) is sufficient for 100 tests.
Features and Benefits
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Physical form
Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Ping Chen et al.
Transplant international : official journal of the European Society for Organ Transplantation, 27(10), 1069-1076 (2014-06-26)
Reduced pretransplant blood myeloid dendritic cell (mDC) levels are associated with post-transplant BK viremia and cytomegalovirus (CMV) disease after kidney transplantation. To elucidate potential mechanisms by which mDC levels might influence these outcomes, we studied the association of mDC levels
Ji Wang et al.
Nature communications, 5, 4447-4447 (2014-07-19)
There is an urgent need of adjuvants for cutaneous vaccination. Here, we report that micro-sterile inflammation induced at inoculation sites can augment immune responses to influenza vaccines in animal models. The inoculation site is briefly illuminated with a handheld, non-ablative
Chanchal Sadhu et al.
Journal of immunoassay & immunochemistry, 29(1), 42-57 (2007-12-18)
Functions and binding properties of four CD11c-specific mAbs are described here. The mAb 496B stimulated, while 496K inhibited ligand binding of CD11c. The stimulatory mAb, 496B, as well as the inhibitory mAbs BU15 and 496 K appear to act allosterically
Akiko Kurishima et al.
Journal of gastroenterology, 49(10), 1367-1377 (2013-10-01)
Dendritic cells (DCs) may play an important role in forms of inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis. DCs are generally recognized as initiators of acquired immunity and also serve as regulators of both innate and
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