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Key Documents

SAB4504580

Sigma-Aldrich

Anti-phospho-EGFR (pSer1071) antibody produced in rabbit

affinity isolated antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 134 kDa

species reactivity

human, mouse, rat

concentration

~1 mg/mL

technique(s)

ELISA: 1:5000
western blot: 1:500-1:1000

NCBI accession no.

P00533

UniProt accession no.

P00533

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer1071)

Gene Information

human ... EGFR(1956)

Immunogen

The antiserum was produced against synthesized peptide derived from human EGFR around the phosphorylation site of Ser1071.

Immunogen Range: 1036-1085

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Javier Palazuelos et al.
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Lakshmi Reddy Bollu et al.
Cell cycle (Georgetown, Tex.), 13(15), 2415-2430 (2014-12-09)
Increased expressions of fatty acid synthase (FASN) and epidermal growth factor receptor (EGFR) are common in cancer cells. De novo synthesis of palmitate by FASN is critical for the survival of cancer cells via mechanisms independent of its role as
Yong Sang Hong et al.
PloS one, 9(10), e109440-e109440 (2014-10-29)
ERBB2-directed therapy is now a routine component of therapy for ERBB2-amplified metastatic gastroesophageal adenocarcinomas. However, there is little knowledge of the mechanisms by which these tumors develop acquired resistance to ERBB2 inhibition. To investigate this question we sought to characterize
X Chen et al.
Neoplasma, 61(5), 514-522 (2014-07-18)
Colorectal cancer (CRC) is the third common cancer and most of the chemotherapies of CRC currently used often suffer limited efficacy and large side effects. Targeted small-molecule by anti-tumor drugs are thought a promising strategy for improving the efficacy and reducing

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