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G5001

Sigma-Aldrich

DL-Glyceraldehyde

≥90% (GC)

Synonym(s):

α,β-Dihydroxypropionaldehyde, 2,3-Dihydroxypropanal

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About This Item

Empirical Formula (Hill Notation):
C3H6O3
CAS Number:
Molecular Weight:
90.08
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

biological source

synthetic

Assay

≥90% (GC)

form

powder

color

white to off-white

mp

145  °C ((293 °F ))

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

room temp

SMILES string

[H]C(=O)C(O)CO

InChI

1S/C3H6O3/c4-1-3(6)2-5/h1,3,5-6H,2H2

InChI key

MNQZXJOMYWMBOU-UHFFFAOYSA-N

General description

Glyceraldehyde is a simple monosaccharide. Based on the number of carbon atoms and the type of carbonyl group present, glyceraldehyde belongs to subgroup triose. It is a colourless and sweet compound.

Application

DL-Glyceraldehyde has been used:
  • as modifying reagent in the preparation of crystallization solution
  • as a substrate to measure aldose reductase activity
  • in the preparation of d/l-glyceraldehyde stock to determine the specific activity of GAPDH (glyceraldehyde 3-phosphate dehydrogenase)

Biochem/physiol Actions

Glyceraldehyde serves as an efficient cross-linking agent and is considered non-toxic. It is an intermediate of a number of metabolic such as glycolysis and pentose phosphate pathway.

Other Notes

DL-Glyceraldehyde is a substrate for the enzyme aldose reductase.
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Gemma Sangüesa et al.
European journal of nutrition, 58(3), 1283-1297 (2018-03-09)
Sugar-sweetened beverage intake is a risk factor for insulin resistance, dyslipidemia, fatty liver, and steatohepatitis (NASH). Sub-chronic supplementation of liquid fructose, but not glucose, in female rats increases liver and plasma triglycerides without inflammation. We hypothesized that chronic supplementation of
Raman and infrared spectroscopy of carbohydrates: a review
Wiercigroch E, et al.
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 185(5), 317-335 (2017)
Chethan Sampath et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 84, 502-513 (2016-09-30)
Hyperglycemic stress activates polyol pathway and aldose reductase (AR) key enzyme responsible for generating secondary complications during diabetes. In this study the therapeutic potential of phloretin, epigallocatechin 3-gallate (EGCG) and [6]-gingerol were evaluated for anti-glycating and AR inhibitory activity in
GAPDH and Intermediary Metabolism
GAPDH: Biological Properties and Diversity, 37-59 (2012)
Stabilization of scleral collagen by glycerol aldehyde cross-linking
N.A.Danilov, et al.
Biochimica et Biophysica Acta, 1780(5), 764-772 (2008)

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