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EHU116301

Sigma-Aldrich

MISSION® esiRNA

targeting human NUCKS1 (2)

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GGGCAGTGAGGAAGAACAAGAAGAGGAGGATGAGGCACCATTCCAGGAGAAAGATTCCGGCAGCGATGAAGATTTCCTAATGGAAGATGATGACGATAGTGACTATGGCAGTTCGAAAAAGAAAAACAAAAAGATGGTTAAGAAGTCCAAACCTGAAAGAAAAGAAAAGAAAATGCCCAAACCCAGACTAAAGGCTACAGTGACGCCAAGTCCAGTGAAAGGCAAAGGGAAAGTGGGTCGCCCCACAGCTTCAAAGGCATCAAAGGAAAAGACTCCTTCTCCCAAAGAAGAAGATGAGGAACCGGAAAGCCCGCCAGAAAAGAAAACATCTACAAGCCCCCCACCCGAGAAATCTGGGGATGAAGGGTCTGAAGATGAAGCCCCTTCTGGGGAGGATTAAAAGTGATGATGGTCTGGGGAGAGA

Ensembl | human accession no.

ENSG00000069275

NCBI accession no.

NM_022731

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... NUCKS1(64710) , NUCKS1(64710)

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ya-Kai Huang et al.
Carcinogenesis, 40(2), 370-379 (2018-10-30)
The effects of nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (NUCKS1) on tumor cells and the relevant mechanisms are less well defined. This study aimed to explore the role and mechanism of action of NUCKS1 in gastric cancer (GC)
Xiaohan Yuan et al.
Journal of cellular physiology (2019-02-03)
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (NUCKS1) is a highly phosphorylated nuclear protein ubiquitously expressed in vertebrates. NUCKS1 has been reported to be a key chromatin modifier and transcriptional regulator of a number of signaling pathways, but the

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