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biological source
plant (Croton tiglium L)
Quality Level
form
viscous liquid
density
0.94 g/mL at 25 °C (lit.)
functional group
ester
lipid type
oils
shipped in
ambient
storage temp.
room temp
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General description
Croton oil is a toxic viscous liquid extracted from seeds of Croton tiglium. It is pale yellow to brown in color and is transparent in nature. Croton oil has a strong irritant property and is used along with phenol in some chemical peels. It also has a tumor promoting ability.
Croton oil is extracted from Croton tiglium L. It consists of crotonoleic acid, crotonic acid, crotonyl alcohol, crotonyl alcohol bisester and crotonyl alcohol trisester. Croton oil acts as a stimulant in the skin and mucosal inflammation. It is associated with allergic contact dermatitis (ACD) and skin carcinoma. Croton oil functions as a skin peeling agent.
Application
Croton oil has been used to induce acute skin inflammation.
Croton oil has been used to induce inflammation in mouse ears.
Other Notes
Essential oil rich in glycerides of saturated fatty acids, and in phorbol esters.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
165.2 °F - closed cup
Flash Point(C)
74 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Gabriella Coruzzi et al.
Experimental dermatology, 21(1), 32-37 (2011-12-14)
The effects of the histamine H(4) receptor antagonist JNJ7777120 were evaluated in a model of acute skin inflammation induced by local application of croton oil. The influence of strain on the effect of JNJ7777120 was investigated in four different mouse
Effects of Haruan (Channa striatus) Based Cream on Acute Inflammation in Croton Oil Induced Mice Ear Edema Model
Abedi S, et al.
Research Journal of Biological Sciences, 7(4), 181-187 (2012)
Bang-Tian Chen et al.
Oxidative medicine and cellular longevity, 2012, 537923-537923 (2012-08-18)
While beneficial health properties of tea leaves have been extensively studied, less attention is paid to the flowers of tea. In this study, the anti-inflammatory effects of hot water extract of tea (Camellia sinensis) flowers were investigated. Pharmacological studies found
Aldair de França-Neto et al.
Natural product communications, 7(10), 1397-1400 (2012-11-20)
Croton argyrophylloides Muell. Arg. is widely used in Brazilian folk medicine to treat diabetes and venereal diseases. This study examined the acute toxicity and cytotoxicity of the essential oil of C. argyrophylloides (EOCA). In addition, vascular effects of the EOCA
Sulaiman Hamizah et al.
Asian Pacific journal of cancer prevention : APJCP, 13(6), 2533-2539 (2012-09-04)
Annona muricata L (Annonaceae), commonly known as soursop has a long, rich history in herbal medicine with a lengthy recorded indigenous use. It had also been found to be a promising new anti-tumor agent in numerous in vitro studies. The
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