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A0263

Sigma-Aldrich

Aflatoxin G2

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About This Item

Empirical Formula (Hill Notation):
C17H14O7
CAS Number:
Molecular Weight:
330.29
Beilstein:
1692017
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

form

powder

Quality Level

storage temp.

2-8°C

SMILES string

[H][C@@]12CCO[C@]1([H])Oc3cc(OC)c4C5=C(C(=O)OCC5)C(=O)Oc4c23

InChI

1S/C17H14O7/c1-20-9-6-10-12(8-3-5-22-17(8)23-10)14-11(9)7-2-4-21-15(18)13(7)16(19)24-14/h6,8,17H,2-5H2,1H3/t8-,17+/m0/s1

InChI key

WPCVRWVBBXIRMA-WNWIJWBNSA-N

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General description

Aflatoxin G2 is a fungal secondary toxic metabolite synthesized by Aspergillus parasiticus, Aspergillus flavus, and Aspergillus nomius, species that are found in tropical and subtropical regions of the world. Aflatoxin Gs (AFGs) are derivatives of difuranocoumarin and contain a bifuran group linked to a coumarin nucleus and a lactone ring.

Application

Aflatoxin G2 has been used as a standard to estimate the levels of aflatoxins by immunoaffinity column cleanup in:
  • peanut confection
  • Ginseng and other roots
  • olive oil, peanut oil, and sesame oil

Biochem/physiol Actions

Aflatoxins are hepatocarcinogenic and act as food contaminants in peanuts, fruits, cereals, corn, and dry fruits.

Warning

Possibly carcinogenic.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Acute Tox. 2 Inhalation - Carc. 1B - Muta. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Dipendra K Mahato et al.
Frontiers in microbiology, 10, 2266-2266 (2019-10-23)
Aflatoxins produced by the Aspergillus species are highly toxic, carcinogenic, and cause severe contamination to food sources, leading to serious health consequences. Contaminations by aflatoxins have been reported in food and feed, such as groundnuts, millet, sesame seeds, maize, wheat
J Tam et al.
Food additives and contaminants, 23(7), 693-699 (2006-06-06)
Three hundred and forty-nine breakfast and infant cereal samples were collected at retail level across Canada from 2002 to 2005. They included rice-, soy-, barley-based and mixed-grain infant cereals, corn-, wheat-, rice-based and mixed-grain breakfast cereals, and were analysed for
M Mably et al.
Food additives and contaminants, 22(12), 1252-1257 (2005-12-17)
Between March 1998 and March 2002, 304 samples of domestic (Canadian) and imported beers from 36 countries were picked up for the determination of aflatoxins B1, B2, G1 and G2. Twelve samples were positive with aflatoxins greater than the limit
Kathleen D'Ovidio et al.
Food additives and contaminants, 23(2), 174-180 (2006-02-02)
Ginseng roots can be infected by molds during growth, harvest and storage and result in contamination with mycotoxins. In this study, an analytical method for the determination of aflatoxins B(1), B(2), G(1) and G(2), a group of structurally similar mycotoxins
Robert A Everley et al.
Journal of analytical toxicology, 31(3), 150-156 (2007-06-21)
Automated immunoaffinity solid-phase extraction followed by liquid chromatography-tandem mass spectrometry and chemical analogue internal standardization is employed to detect and quantify the aflatoxins AFB(1), AFB(2), AFG(1), AFG(2), and the metabolites AFM(1) and AFP(1) in urine. The dynamic range of the

Articles

Carcinogenesis and Epigenetics

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