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Key Documents

S8170

Sigma-Aldrich

Sodium nitrate

BioXtra, ≥99.0%

Synonym(s):

Chile salpeter

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About This Item

Empirical Formula (Hill Notation):
NaNO3
CAS Number:
Molecular Weight:
84.99
EC Number:
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.25

product line

BioXtra

Quality Level

Assay

≥99.0%

impurities

<0.0005% Phosphorus (P)
<0.1% Insoluble matter

mp

306 °C (dec.) (lit.)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): <0.05%
sulfate (SO42-): <0.05%

cation traces

Al: <0.0005%
Ca: <0.0005%
Cu: <0.0005%
Fe: <0.0005%
K: <0.01%
Mg: <0.0005%
NH4+: <0.1%
Pb: <0.001%
Zn: <0.0005%

SMILES string

[Na+].[O-][N+]([O-])=O

InChI

1S/NO3.Na/c2-1(3)4;/q-1;+1

InChI key

VWDWKYIASSYTQR-UHFFFAOYSA-N

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General description

Sodium nitrate is synthesized by treating nitrite with nitric acid. The proportion of nitrite production is higher when synthesized by absorbing waste gases from nitric acid. Supplementation of sodium nitrate may serve to improve acute heart failure (AHF) by modulating the nitric oxide precursor levels.

Application

Sodium nitrate has been used:
  • in combination with beef extract for virus elution from water samples
  • as an external calibrant in nitrate assay to quantify nitrate in cell culture medium
  • as a component of liquid BG11-medium for culturing Synechococcus elongatus PCC 7942
  • to test its protective effects in hepatic ischemia-reperfusion injury

Pictograms

Flame over circleExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Ox. Sol. 3

Storage Class Code

5.1B - Oxidizing hazardous materials

WGK

WGK 1

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Two-step concentration of complex water samples for the detection of viruses
Farkas K, et al.
Methods and Protocols, 1(3), 35-35 (2018)
Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver
Duranski MR, et al.
The Journal of Clinical Investigation, 115(5), 1232-1240 (2005)
Inorganic nitrate as a treatment for acute heart failure: a protocol for a single center, randomized, double-blind, placebo-controlled pilot and feasibility study
Falls R, et al.
Journal of Translational Medicine, 15(1), 172-172 (2017)
Re-evaluation of sodium nitrate (E 251) and potassium nitrate (E 252) as food additives
Mortensen A, et al.
EFSA Journal, 15(6), e04787-e04787 (2017)
Quantification of Chlorophyll as a Proxy for Biofilm Formation in the Cyanobacterium Synechococcus elongatus
Sendersky E, et al.
Bio-protocol, 7, e2406-e2406 (2017)

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