PHR1704

Nafcillin Sodium

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Nafcillin sodium salt monohydrate, 6-(2-Ethoxy-1-naphthamido)penicillin
• Linear Formula: C₂₁H₂₁N₂O₅SNa · H₂O
• CAS Number: 7177-50-6
• Molecular Weight: 454.47
• MDL number: MFCD01941128
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823567
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to USP 1450007
• API family: nafcillin
• CofA: current certificate can be downloaded
• packaging: pkg of 1 g
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: -10 to -25°C
• SMILES string: O.[Na+].CCOc1ccc2ccccc2c1C(=O)N[C@H]3C4SC(C)(C)[C@@H](N4C3=O)C([O-])=O
• InChI: 1S/C21H22N2O5S.Na.H2O/c1-4-28-13-10-9-11-7-5-6-8-12(11)14(13)17(24)22-15-18(25)23-16(20(26)27)21(2,3)29-19(15)23;;/h5-10,15-16,19H,4H2,1-3H3,(H,22,24)(H,26,27);;1H2/q;+1;/p-1/t15-,16+,19-;;/m1../s1
• InChI key: OCXSDHJRMYFTMA-KMFBOIRUSA-M

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Nafcillin Sodium is a narrow-spectrum β-lactamase resistant antibiotic drug.

Application

Nafcillin Sodium may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H315 - H317 - H319 - H334 - H335
• Precautionary Statements: P261 - P280 - P284 - P304 + P340 - P305 + P351 + P338 - P342 + P311
• Hazard Classifications: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable