PHL89716

Indirubin

phyproof^® Reference Substance

• Synonym(s): Coroupitine B, Indigo Red, Indigopurpurin
• Empirical Formula (Hill Notation): C₁₆H₁₀N₂O₂
• CAS Number: 479-41-4
• Molecular Weight: 262.26
• MDL number: MFCD00221745
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: primary reference standard
• product line: phyproof^® Reference Substance
• Assay: ≥95.0% (HPLC)
• manufacturer/tradename: PhytoLab
• application(s): food and beverages
• format: neat
• storage temp.: −20°C
• InChI: 1S/C16H10N2O2/c19-15-10-6-2-4-8-12(10)17-14(15)13-9-5-1-3-7-11(9)18-16(13)20/h1-8,17H,(H,18,20)/b14-13+
• InChI key: CRDNMYFJWFXOCH-BUHFOSPRSA-N

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application

• Indirubin for leukemia treatment: Indirubin′s role as a kinase inhibitor positions it as a potential therapeutic in leukemia treatment. Its inhibition of cyclin-dependent kinases suggests utility in cell cycle regulation, which is pivotal in leukemia pathology. Research highlights its capabilities to modulate kinase activity, providing a pathway to targeted cancer therapies (Wang et al., 2024).


• Indirubin in cancer research: As an anti-cancer agent, Indirubin demonstrates efficacy in vitro, particularly in inducing apoptosis in cancer cells. Its interaction with cellular signaling pathways enhances its potential as a therapeutic agent in various cancers, underlining its importance in oncological studies (Li et al., 2024).


• Indirubin for neurodegenerative disease study: Exploring Indirubin′s effects on neurodegenerative diseases, recent studies focus on its neuroprotective properties through the regulation of kinase signaling pathways. This research underpins its therapeutic potential in diseases like Alzheimer′s and Parkinson′s, indicating its broad applicability in neurology (Li et al., 2024).

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable