G5767

D-(+)-Glucose

ACS reagent

• Synonym(s): Dextrose
• Empirical Formula (Hill Notation): C₆H₁₂O₆
• CAS Number: 50-99-7
• Molecular Weight: 180.16
• Beilstein: 1724615
• EC Number: 200-075-1
• MDL number: MFCD00063774
• UNSPSC Code: 12352201
• PubChem Substance ID: 24895228
• NACRES: NA.21

Properties

• biological source: wheat
• Quality Level: 200
• grade: ACS reagent
• form: powder
• optical activity: [α]25/D +52.5 to +53.0°(lit.)
• impurities: Starch, passes test; ≤0.002 meq/g Titratable acid; ≤0.005% Insoluble matter
• ign. residue: ≤0.02%
• loss: ≤0.2% loss on drying, 105°C
• color: colorless
• mp: 150-152 °C (lit.)
• anion traces: chloride (Cl^-): ≤0.01%; sulfate, sulfite (as SO₄^2-): ≤0.005%
• cation traces: Fe: ≤5 ppm; heavy metals (as Pb): ≤5 ppm
• storage temp.: room temp
• SMILES string: OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
• InChI key: WQZGKKKJIJFFOK-DVKNGEFBSA-N
• Gene Information: human ... PYGM(5837)

Description

General description

D-glucose, an aldohexose, possesses four chiral carbon atoms. It is an important product obtained from starch hydrolyzed by acid and/or enzymes.

Application

D-(+)-Glucose has been used:

• as a supplement in Dulbecco′s phosphate-buffered saline (DPBS) for standardized serum bactericidal assay (SBA) using human complement
• as a component in 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES)-buffered Tyrode′s solution to treat the excised diaphragmatic specimens to assess the effect of osmolarity changes on the intrinsic lymphatic pumping mechanism
• to study the effect of restoring circulating glucose content in insulin-responsive neurons of rats
• for oral glucose tolerance tests (OGTTs)

Biochem/physiol Actions

Glucose, the universal energy source for all human cells, is the vital precursor for the production and conversion of several downstream carbohydrates. The uptake of glucose is a key indicator of cellular energy metabolism. Glucose infusion can block the release of oxytocin and vasopressin by insulin-induced hypoglycemia in humans.

Preparation Note

The material may produce a yellowish solution if prepared at a higher concentration than 2 g + 15mL.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves