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BCR266

7H-Dibenzo[c,g]carbazole

BCR®, certified reference material

Synonym(s):

3,4,5,6-Dibenzocarbazole

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About This Item

Empirical Formula (Hill Notation):
C20H13N
CAS Number:
194-59-2
Molecular Weight:
267.32
Beilstein:
213015
MDL number:
MFCD00215941
PubChem Substance ID:
329773800
NACRES:
NA.24

grade

certified reference material

Agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

environmental
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[H]n1c2ccc3ccccc3c2c4c1ccc5ccccc45

InChI

1S/C20H13N/c1-3-7-15-13(5-1)9-11-17-19(15)20-16-8-4-2-6-14(16)10-12-18(20)21-17/h1-12,21H

InChI key

STJXCDGCXVZHDU-UHFFFAOYSA-N

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Analysis Note

For more information please see:
BCR266

Legal Information

BCR is a registered trademark of European Commission

Pictograms

Exclamation markHealth hazard
GHS07,GHS08

Signal Word

Warning

Hazard Statements

H302 - H319 - H351

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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J Laitakari et al.
Toxicologic pathology, 29(5), 514-527 (2001-11-07)
Intratracheal instillations of 7H-dibenzo(c, g)carbazole (DBC), a tobacco smoke component, into Syrian golden hamsters, resulted in preneoplastic lesions and benign and malignant respiratory neoplasms. Neoplastic progression was associated with specific changes in the extracellular matrix (ECM), dependent on the stage
D L Gray et al.
Experimental lung research, 27(3), 245-253 (2001-04-11)
Polycyclic aromatic hydrocarbons (PAH) and N-heterocyclic aromatic hydrocarbons (NHA) are environmental pollutants formed during the incomplete combustion of organic materials. Benzo(a)pyrene (BaP) and 7H-dibenzo(c,g)carbazole (DBC) are well-characterized representatives of the PAH and NHA classes of compunds, respectively. Both are demonstrated
Jan Vondrácek et al.
Mutation research, 596(1-2), 43-56 (2006-01-13)
Immature liver progenitor cells have been suggested to be an important target of hepatotoxins and hepatocarcinogens. The goal of the present study was to assess the impact of 7H-dibenzo[c,g]carbazole (DBC) and its tissue-specific carcinogenic N-methyl (N-MeDBC) and 5,9-dimethyl (DiMeDBC) derivatives
Alena Gábelová et al.
Environmental and molecular mutagenesis, 52(8), 636-645 (2011-08-03)
The goal of this study was to investigate the genotoxicity of 7H-dibenzo[c,g]carbazole (DBC), a ubiquitous environmental pollutant, and its methyl derivatives, 5,9-dimethylDBC (DiMeDBC), a strict hepatocarcinogen, and N-methylDBC (N-MeDBC), a specific sarcomagen in human hepatoma HepG2 cells, and to infer
Weiling Xue et al.
Chemical research in toxicology, 15(7), 915-921 (2002-07-18)
7H-dibenzo[c,g]carbazole (DBC) is a potent multispecies, multisite carcinogen present in the environment. The metabolic activation pathways of DBC are not completely known. It is hypothesized that DBC may be metabolically activated by oxidation to the reactive Michael acceptor o-quinones, which
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