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909513

Sigma-Aldrich

3-Azido-7-hydroxycoumarin

≥95%

Synonym(s):

3-Azido-7-hydroxy-chroman-2-one, 3-Azido-7-hydroxy-chromen-2-one

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About This Item

Empirical Formula (Hill Notation):
C9H5N3O3
CAS Number:
817638-68-9
Molecular Weight:
203.15
MDL number:
MFCD12924840
UNSPSC Code:
12352202

Assay

≥95%

form

solid

availability

available only in USA

storage temp.

−20°C

InChI

1S/C9H5N3O3/c10-12-11-7-3-5-1-2-6(13)4-8(5)15-9(7)14/h1-4,13H

InChI key

KKJNQKVCZCNJDI-UHFFFAOYSA-N

Application

This special UV active chromophore is ideal for imaging purposes after conjugation to biomolecules. It emits fluorescence only after the click reaction when its electron system is expanded. Therefore no background signal is expected for the unreacted compound. λabs 404 nm (after click reaction), λem 477 nm (after click reaction ).

Pictograms

Flame
GHS02

Signal Word

Danger

Hazard Statements

H242

Hazard Classifications

Self-react. C

Storage Class Code

5.2 - Organic peroxides and self-reacting hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Scott T Laughlin et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(1), 12-17 (2008-12-24)
Molecular imaging enables visualization of specific molecules in vivo and without substantial perturbation to the target molecule's environment. Glycans are appealing targets for molecular imaging but are inaccessible with conventional approaches. Classic methods for monitoring glycans rely on molecular recognition

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