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30-0901

Sigma-Aldrich

Tetrahydrofuran

≥99.0%, SAJ first grade, contains BHT as stabilizer

Synonym(s):

THF, Butylene oxide, Oxolane, Tetramethylene oxide

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About This Item

Empirical Formula (Hill Notation):
C4H8O
CAS Number:
109-99-9
Molecular Weight:
72.11
Beilstein:
102391
MDL number:
MFCD00005356
UNSPSC Code:
12352005
PubChem Substance ID:
329753428

product name

Tetrahydrofuran, SAJ first grade, ≥99.0%

grade

SAJ first grade

vapor density

2.5 (vs air)

vapor pressure

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

Assay

≥99.0%

form

liquid

autoignition temp.

610 °F

contains

BHT as stabilizer

expl. lim.

1.8-11.8 %

availability

available only in Japan

refractive index

n20/D 1.407 (lit.)

pH

~7

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

density

0.889 g/mL at 25 °C (lit.)

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

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Application



  • Buffer systems for environmental toxicology: A study utilized buffer concentrates within a tiered regulatory framework for aquatic risk assessment of pesticides, emphasizing the critical role of standardized buffer systems in maintaining consistent experimental conditions (Santos et al., 2024).


  • Buffer concentrate in pharmaceutical formulations: Buffer concentrates were used in the development of a prolonged permeation in situ gel for Levofloxacin HCl-Salicylic Acid, underlining the importance of buffer systems in drug release modulation and stability (Khaing et al., 2024).


  • Buffer concentrate in diagnostic assays: The formulation of lateral flow devices for the detection of urinary biomarkers in kidney health assessments incorporated buffer concentrates to ensure optimal reagent performance and reaction kinetics (D Souza et al., 2024).


Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2

Supplementary Hazards

EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

5.9 °F

Flash Point(C)

-14.5 °C

Certificates of Analysis (COA)

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Han Yan et al.
Advanced materials (Deerfield Beach, Fla.), 27(23), 3484-3491 (2015-05-06)
Polymer solar cells are fabricated with systematic variation of the phase purity. Photovoltaic tests demonstrate that devices with ca. 10% of mixed phases outperform pure-phase devices. Photophysical studies reveal the effects of mixed phase on charge generation and recombination. These
Ryan D Pensack et al.
Journal of the American Chemical Society, 137(21), 6790-6803 (2015-05-07)
We compare the singlet fission dynamics of five pentacene derivatives precipitated to form nanoparticles. Two nanoparticle types were distinguished by differences in their solid-state order and kinetics of triplet formation. Nanoparticles that comprise primarily weakly coupled chromophores lack the bulk
Luca Chiari et al.
The Journal of chemical physics, 138(7), 074301-074301 (2013-03-01)
We present total, elastic, and inelastic cross sections for positron and electron scattering from tetrahydrofuran (THF) in the energy range between 1 and 5000 eV. Total cross sections (TCS), positronium formation cross sections, the summed inelastic integral cross sections (ICS)
P T Clayton et al.
The Journal of clinical investigation, 79(4), 1031-1038 (1987-04-01)
Urinary bile acids from a 3-mo-old boy with cholestatic jaundice were analyzed by ion exchange chromatography and gas chromatography-mass spectrometry (GC-MS). This suggested the presence of labile sulfated cholenoic acids with an allylic hydroxyl group, a conclusion supported by analysis
C N Ong et al.
British journal of industrial medicine, 48(9), 616-621 (1991-09-01)
Occupational exposure to tetrahydrofuran (THF) was studied by analysis of environmental air, blood, alveolar air, and urine from 58 workers in a video tape manufacturing plant. Head space gas chromatography (GC) with an FID detector was used for determination of
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