444270

MMP-7, Active, Human, Recombinant, E. coli

• Synonym(s): Matrilysin, rhMMP-7, PUMP-1
• Enzyme Commission number: 3.4.24.23 (BRENDA, IUBMB)
• UNSPSC Code: 12352202
• NACRES: NA.77

Properties

• form: liquid
• Quality Level: 100
• specific activity: ≥3000 units/mg protein
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• shipped in: wet ice
• storage temp.: −70°C

Description

General description

Recombinant, human MMP-7 expressed in E. coli. MMP-7, the smallest member of the matrix metalloproteinase family that can degrade a wide range of gelatins, proteoglycans, and glycoproteins of the matrix and can activate several other MMPs.

Recombinant, human MMP-7 expressed in E. coli. MMP-7 is the smallest member of the matrix metalloproteinase family that can degrade a wide range of gelatins, proteoglycans, and glycoproteins of the matrix and activate several other MMPs.

Warning

Toxicity: Standard Handling (A)

Unit Definition

One unit is defined as the amount of enzyme that will digest 1.0 µg AZOCOLL Substrate (Cat. No. 194933) per min at 37°C, pH 7.5.

Physical form

In 150 mM NaCl, 10 mM HEPES, 5 mM CaCl₂, pH 7.4.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Other Notes

Kivelä-Rajamäki, M., et al. 2003. J. Periodont. Res.38, 583.
Woessner, J.F. 1995. Methods Enzymol. 248, 485.
Crabbe, T., et al. 1992. Biochemistry 31, 8500.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable